Glowing biomolecule translocating through a 3 nm single nanomembrane in a solid-state nanomembrane separating cis and trans chambers with ion current flow

Last Updated on August 2, 2026 by Staff

Scientists have made a discovery. They have created a small sensor that can detect molecules and remember what it detected before. This is a deal because it could lead to new technologies that are smarter and more advanced.

The scientists who did this research are from SANKEN at the University of Osaka and other places. They published their findings in ACS Nano.

This new sensor is different from the ones. It can change its shape and structure as it detects molecules. This means it can send signals and store information about what it detected.

The scientists think this could be big for tests, biology research and new technologies that use ions instead of electrons.

What Is a Nanopore?

A nanopore is a small hole. It is a few billionths of a meter wide. Scientists use nanopores to identify molecules like DNA, proteins and amino acids.

When a molecule goes through the pore it changes the flow of current. By measuring these changes scientists can figure out what molecule it is. Old nanopores are not very smart. They just sit there. Do not change.

The new nanopore is different. It changes its shape and structure by itself.

Self-Changing Sensor

The scientists made the nanopore so it would work with an electrical voltage. Inside the pore chemical reactions happen over and over again. These reactions make tiny mineral deposits form and dissolve.

This makes the nanopore open and close by itself. Each time it opens and closes it sends signals. Because the nanopore is always changing every molecule that goes through it affects the chemical reactions.

So the sensor does not just detect molecules. It also changes its behavior based on what it detects. This makes the sensor very smart and able to adapt to its surroundings.

Memory Matters

The new nanopore has a kind of memory. It remembers the molecules that went through it before. Each molecule that goes through the pore affects the signals and the pores future behavior.

The scientists used computer programs to analyze the signals. They were able to identify DNA molecules and amino acids. This is big because the nanopore can do all this without anyone controlling it.

Future Applications

The scientists think this technology is a step forward. Nanopores could become systems that can learn and respond to their environment. This could lead to medical tests and biology research. It could also lead to technologies that use ions instead of electrons.

The scientists are excited about the possibilities. They think this could lead to advances, in many fields.

They also think that molecular sensors do not have to sit there and detect things. They can interact with their environment, remember what happened before and make decisions.

This could make technology like living things and that is a big deal.

Read the press release here 


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Health and Chemistry